1) It is recommended to be careful not to separate the washing and Berachah on the bread in any way. It is correct not to separate them even with a short waiting period without speaking. One should definitely not interrupt with speech, even for Divrei Torah. (Shulchan Aruch and Mishne Berura 163)

2) However, even in the event that one has already waited a long time or interrupted with speech, he is not obligated to wash again, unless he has stopped making sure that his hands stay clean. (ibid and Kitzur Shulchan Aruch)